Higher neuronal discharge rate in the motor area of the subthalamic 1 nucleus of Parkinsonian patients
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چکیده
nucleus of Parkinsonian patients 2 Marc Deffains , Peter Holland , Shay Moshel , Fernando Ramirez de Noriega , 3 Hagai Bergman 1,2 & Zvi Israel 5 4 1 Department of Medical Neurobiology, The Hebrew University-Hadassah Medical 5 School, Jerusalem, 91120, Israel 6 2 The Edmond and Lily Safra Center for Brain Sciences, The Hebrew University, 7 Jerusalem, 91904, Israel 8 3 Alpha Omega Engineering Ltd, Nazareth, 1612102, Israel 9 4 The Research Laboratory of Brain Imaging and Stimulation, The Jerusalem Mental 10 Health Center, Kfar-Shaul Etanim, The Hebrew University-Hadassah Medical School, 11 Jerusalem, 91060, Israel 12 5 Center for Functional and Restorative Neurosurgery, Department of Neurosurgery, 13 Hadassah University Hospital, Jerusalem, 91120, Israel 14 * Equal contribution 15 16 Corresponding author : Marc Deffains 17 Department of Medical Neurobiology (physiology), The Hebrew University-Hadassah 18 Medical School, POB 12272, Jerusalem, 91120, Israel. Email: [email protected] 19 20 Abbreviated title : Abnormal subthalamic discharge rate 21 22 23 Articles in PresS. J Neurophysiol (June 11, 2014). doi:10.1152/jn.00170.2014
منابع مشابه
Higher neuronal discharge rate in the motor area of the subthalamic nucleus of Parkinsonian patients.
In Parkinson's disease, pathological synchronous oscillations divide the subthalamic nucleus (STN) of patients into a dorsolateral oscillatory region and ventromedial nonoscillatory region. This bipartite division reflects the motor vs. the nonmotor (associative/limbic) subthalamic areas, respectively. However, significant topographic differences in the neuronal discharge rate between these two...
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